SEROTONIN RL
Serotonin Release Assay
EPIC Test Procedure Code: LAB4022
Synonyms:
Unfractionated Heparin-Dependent Platelet Antibody
SRAU
Performing Lab:
Referral Laboratory
Patient Preparation:
1. Specimen should be collected from a fasting (preferred but not required) patient during an episode of suspected heparin-induced thrombocytopenia.
2. Patient should not be on ticagrelor (Brilinta) as this may interfere with the assay, yielding a false-negative result.
Container Type:
Plain red top (NO GEL TUBES)
Specimen Type:
Serum
Preferred Volume:
1.0 mL
Minimum Volume:
1.0 mL
Specimen Processing:
1. After collection, specimen should sit at ambient temperature for a minimum of 1 hour in order to clot completely.
2. Centrifuge and aliquot serum into a plastic vial.
Store and Transport:
Frozen
Stability:
Refrigerated- 7 Days
Frozen (Preferred)- 2 years
Unacceptable Condition:
Gross Lipemia: Reject
CPT Codes:
82542 - Serotonin Release Assay (EAP 99935081)
Test Schedule:
Monday through Friday
Turnaround Time:
2-5 Days
Method:
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)