NGS FOR MYELOID NEOPLASMS
NGS for Myeloid Neoplasms
EPIC Test Procedure Code: LAB6615
Synonyms:
Next-Generation Sequencing for Myeloid Neoplasms
CSF3R Exon 14 and 17 Mutation Detection
Performing Lab:
Referral Laboratory
Container Type:
Lavender top (EDTA) tube or ACD (yellow top)
Specimen Type:
Blood or bone marrow
Preferred Volume:
3.0 mL Blood
2.0 mL Bone Marrow
2.0 mL Bone Marrow
Alternate Specimens:
Sodium Heparin (green top)
Minimum Volume:
1.0 mL
Specimen Processing:
Peripheral blood and bone marrow specimens must arrive at Mayo within 14 days of collection.
Store and Transport:
Ambient (preferred)/Refrigerate
Stability:
Room Temperature: 14 days
Refrigerated: 14 days
Unacceptable Condition:
Gross hemolysis, moderately to severely clotted samples, bone marrow biopsies, paraffin-embedded tissues or paraffin-embedded bone marrow aspirates.
CPT Codes:
81450 - NGS for Myeloid Neoplasms; 5-50 Genes (EAP 31032203)
Turnaround Time:
2-3 weeks
Method:
Somatic Mutation Detection by Next-Generation Sequencing (NGS)
Test Includes:
This test includes next-generation sequencing to evaluate for the following 42 genes and select intronic regions: ANKRD26, ASXL1, BCOR, CALR, CBL, CEBPA, CSF3R, DDX41, DNMT3A,ELANE, ETNK1, ETV6, EZH2, FLT3, GATA1, GATA2, IDH1, IDH2, JAK2, KDM6A, KIT, KRAS, MPL, NPM1, NRAS, PHF6, PTPN11, RAD21, RUNX1, SETBP1, SH2B3, SF3B1, SRP72, SMC3, SRSF2, STAG2,TERT, TET2, TP53, U2AF1, WT1, and ZRSR2.
Reference Ranges:
Reflex Test :