Cardiovascular research continues to be a major focus at Saint Luke’s Health System. The program currently encompasses research programs in each of the major clinical areas, including:

  • Interventional cardiology
  • Cardiac surgery
  • Heart failure
  • Cardiac transplantation
  • Cardiac electrophysiology
  • Cardiac imaging
  • Preventive cardiology/lipid
  • Diabetes management
  • Adult congenital heart disease

Hundreds of patients enroll in these programs annually for a broad range of randomized trials and registry-based research studies, making the programs essential to the mission of Saint Luke’s Mid America Heart Institute. Research allows the Heart Institute to remain on the leading edge of cardiovascular care. In addition to these clinical research programs, many Heart Institute cardiologists participate in research through the Ben D. McCallister Clinical Scholars Program, which provides funding and support for investigator-initiated studies.

In addition to supporting clinical research, the cardiovascular research program encompasses centers of excellence and core laboratories in cardiovascular outcomes research, health economics and technology assessment, intravascular imaging, and noninvasive imaging. These centers of excellence currently serve as core laboratories for a wide range of studies that often involve collaboration with other leading cardiovascular centers and researchers from around the world. The Heart Institute continues to serve as one of the four Analytic Centers, along with Duke, Harvard, and Yale, for the American College of Cardiology’s National Cardiovascular Data Registry.

Contact Us

For more information, call 816-932-4581.


Heart Valve Replacement without Invasive Surgery
Rosemary stopped her regular walk to Loose Park to admire the roses. Taking more than 20 steps robbed her of breath and tightened her chest with pain.
Symplicity trial evaluates effectiveness of high blood pressure treatment

High blood pressure, or hypertension, is the single most common contributor to death worldwide and a major risk factor for stroke, heart attack, co

Saint Luke’s cardiologist honored with prestigious American Heart Association award
Cardiologist John Spertus, M.D., M.P.H., has been named the recipient of the American Heart Association’s Council on Quality of Care and Outcomes Research (QCOR) Distinguished Achievement Award for contributions to the field.
Fatty liver disease stronger independent indicator of cardiovascular disease than age, smoking, gender, or other traditional risk factors

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in the United States and other Western countries, affecting up to a thir

Saint Luke's awarded $3.4 million grant from Boston Scientific for further research into innovative cardiac procedures

Saint Luke's Mid America Heart Institute has been awarded a $3.4 million, three-year grant from Boston Scientific to investi

Alcohol and Cardiovascular Health: The Dose Makes the Poison or the Remedy
Researchers reviewed studies focused on alcohol, ethanol, cardiovascular disease, coronary artery disease, heart failure, hypertension, stroke, and mortality.
Peripheral Artery Disease: Get a Leg Up

Theresa might not be walking on two legs, much less doing Pilates, if it weren’t for cardiovascular surgeon

Omega-3 and Prostate Cancer: Examining the Pertinent Evidence
Consumption of long chain omega-3 fatty acids – from fish oil and fish oil supplements – have long been considered to provide a variety of health benefits.
David J. Cohen, M.D., M.Sc. and John A. Spertus, M.D., M.P.H., named as two of the World’s Most Influential Scientific Minds 2014
David J. Cohen, M.D., M.Sc., and John A. Spertus, M.D., M.P.H., cardiologists with Saint Luke’s Mid America Heart Institute in Kansas City and the University of Missouri – Kansas City, have dedicated their professional lives to cardiovascular research, producing innovative and impactful science that has defined and shaped cardiovascular care across the country.
KCTV: Saint Luke's Mid America Heart Institute Implants World's Tiniest Pacemaker

KCTV5's Bonyen Lee was present when Saint Luke's Mid America Heart Institute physicians implanted the world's tiniest pacemaker.

Precision Medicine Improves Use of Bleeding Avoidance Strategies and Reduces Bleeding in Patients Undergoing Percutaneous Coronary Intervention
Researchers at Saint Luke’s Mid America Heart Institute asked the question whether prospectively determining and informing physicians of an individual patient’s bleeding risk would increase the proper application of bleeding avoidance strategies and result in reduced odds of bleeding.
FOX4: Saint Luke's Mid America Heart Institute Research Examines the Impact of Quitting Smoking on Heart Attack Patient Outcomes
New research out of Saint Luke's Mid America Heart Institute indicates quitting smoking even after a heart attack can have a positive impact on a patient's health and ultimate outcome.
Therapeutic Hypothermia may not be beneficial in an in-hospital setting
While therapeutic hypothermia may help improve some outcomes in patients whose hearts stop suddenly outside the hospital, it doesn't appear to provide benefit when cardiac arrest happens in a hospital setting, according to a study published in the Journal of the American Medical Association.
FOX4: A simple vest could help heart failure patients stay out of the hospital
Having fluid in your lungs can feel just like drowning. It's a big problem for people with congestive heart failure. Now a vest is helping some people monitor their fluid levels and potentially stay out of the hospital.