REF MISC
NGS for Multiple Myeloma
Synonyms:
NGS MM
Performing Lab:
Referral Laboratory
Container Type:
Lavender top (EDTA) or yellow top (ACD) tube
Specimen Type:
Bone Marrow
Preferred Volume:
2 mL
Alternate Specimens:
Paraffin block or Tissue slides from bone marrow clot. Minimum amount of plasma cells is 20%. See Mayo's website for more specific information.
Minimum Volume:
1 mL
Specimen Processing:
Fresh specimen is required for this test!
Store and Transport:
Room Temperature
Stability:
Room Temperature (Preferred): 4 days
Refrigerated: 4 days
CPT Codes:
81450
Reflex: 88184, 88185x5
Method:
Next-Generation Sequencing (NGS)
Test Includes:
This test includes next-generation sequencing to evaluate the following 26 genes and select intronic regions: BIRC3, BRAF, CCND1, CDKN2A, CRBN, CUL4A, CUL4B, CXCR4, DIS3, EGFR, IDH1, IDH2, IKZF1, IKZF3, KRAS, MYC, MYD88, NRAS, NSD2, PIK3CA, PIM1, STAT3, TENT5C, TP53, TRAF3, and XBP1.
Reference Ranges:
Reflex Test :