Provider Profile

James H O'Keefe, Jr, MD
Saint Luke’s Care Member

Provider Profile

James H O'Keefe, Jr, MD

Cardiology
Call to make an appointment 816-931-1883

Education

Medical School
Univ of North Dakota School of Medicine, Grand Forks, ND
Medical School
Baylor College of Medicine, Houston, TX
Residency
Med/Internal, Mayo Graduate School of Medicine, Rochester, MN
Fellowship
Med/Cardiology, Mayo Graduate School of Medicine, Rochester, MN

Board Certifications

  • American Board of Internal Medicine
  • American Board of Internal Medicine - Subspecialty in Cardiovascular Disease

Academic Titles

  • Associate Clinical Professor, University of Missouri–Kansas City School of Medicine

Clinical Interests

  • preventative cardiology
  • nuclear cardiology
  • clinical cardiology

Biography

James H O'Keefe, MD, is a cardiologist and Medical Director of the Charles and Barbara Duboc Cardio Health & Wellness Center at Saint Luke’s Mid America Heart Institute. He is a Professor of Medicine at the University of Missouri-Kansas City. His postgraduate training includes a cardiology fellowship at Mayo Clinic in Rochester, Minnesota. Dr. O’Keefe is board-certified in Cardiology, Internal Medicine, Nuclear Cardiology, and Cardiac CT Imaging. He is consistently ranked among the regional ‘Top Doctor’ lists and has  been named as one of USA Today’s Most Influential Doctors.  Dr. O’Keefe has contributed more than 250 articles to medical literature and has authored best-selling cardiovascular books for health professionals including: The Complete Guide to ECGs, Dyslipidemia Essentials, and Diabetes Essentials. He lectures extensively on the role of therapeutic lifestyle changes and drug therapy in cardiovascular risk reduction. Dr. O’Keefe has co-authored, with his wife Joan, the best-selling consumer health book, The Forever Young Diet and Lifestyle. He is actively involved in patient care and research.

News

New York Times: The Best Sport for a Longer Life? Try Tennis
A new landmark study shows social sport can help your longevity. “Raising your heart rate is important” for health, Dr. James O'Keefe says. “But it looks like connecting with other people is, too.”
TIME: Do This Kind of Exercise If You Want to Live Longer, Study Says

A new landmark study evaluated the different improvements in life expectancy associated with participation in various sports.

Accepted Insurances

  • Aetna Choice POS II
  • Aetna Choice POS II Aexcel Local
  • Aetna Choice POS II Local
  • Aetna Elect Choice
  • Aetna Federal Employees Health Benefit Plan
  • Aetna HMO
  • Aetna HMO Local
  • Aetna Mail Handlers Benefit Plan
  • Aetna Managed Choice
  • Aetna MDOT & Missouri State Highway Patrol
  • Aetna Medicare
  • Aetna Missouri Preferred
  • Aetna MU myChoice Health Program
  • Aetna Open Choice PPO
  • Aetna Select
  • Aetna Select Local
  • Aetna Signature Administrators (ASA)
  • Aetna Workers Comp
  • BCBS of Kansas (call provider)
  • BCBS of Kansas City (PPO)
  • BCBS of Kansas City Freedom Network
  • BCBS of Kansas City Freedom Network Select
  • BCBS of Kansas City Preferred Care
  • BCBS of Kansas City Preferred Care Blue
  • BCBS of Kansas City Traditional
  • Century Health Solutions (PPO)
  • Cigna (HMO)
  • Cigna (Open Access)
  • Cigna (PPO)
  • CompResults (WC)
  • Coventry Advantra Freedom (PPO)
  • Coventry Health and Life Insurance Company
  • Coventry Health Care
  • Coventry Medicare Advantra (PPO)
  • Golden Rule
  • Health Choice of Northwest Missouri (PPO)
  • Healthcare USA-MC+ (Aetna Better Health)
  • HealthLink (HMO)
  • HealthLink (PPO) through Freedom Network
  • Home State Health Plan (Missouri practices)
  • Humana (PPOx)
  • Humana Choice Care (PPO)
  • Humana Choice PPO (Medicare Advantage PPO)
  • Humana Gold Choice Medicare Advantage PFFS
  • Humana Gold Plus (HMO)
  • Humana Gold Plus HMO SNP
  • Humana SmartExpress PPO
  • Humana SmartNet PPO
  • Humana SmartSuite PPO
  • HumanaOne
  • Integrated Health Plan
  • Kansas Medicaid
  • Medicare
  • Missouri Care (Missouri practices only)
  • Missouri Medicaid
  • MultiPlan/PCHS (PPO)
  • Occupational Health Management (WC)
  • OHARA Managed Care (WC)
  • ProviDRs Care Network (formerly WPPA)
  • Pyramid Life (Medicare Advantage PPO)
  • Railroad Medicare
  • Sunflower State Health Plan (Kansas practices)
  • TRICARE
  • Triwest Veterans Affairs Patient Centered Community Care
  • United Healthcare Choice
  • United Healthcare Choice Plus
  • United Healthcare Community Plan
  • United Healthcare Definity Health Reimbursement Account
  • United Healthcare Definity Health Savings Account
  • United Healthcare Golden Rule HMO
  • United Healthcare Indemnity
  • United Healthcare Managed Indemnity
  • United Healthcare Options PPO
  • United Healthcare Select
  • United Healthcare Select Plus
  • UnitedHealthcare Evercare DH
  • UnitedHealthcare Evercare DH-POS
  • UnitedHealthcare Evercare DP
  • UnitedHealthcare Evercare RDP
  • UnitedHealthcare Medicare Choice
  • UnitedHealthcare Medicare Choice Essential
  • UnitedHealthcare Medicare Complete
  • UnitedHealthcare Medicare Complete Essential
  • UnitedHealthcare Medicare Complete Plus
  • UnitedHealthcare Medicare DH
  • UnitedHealthcare Medicare Plus Essential
  • US Department of Labor

Publications

 

BOOK CHAPTERS & MONOGRAPHS:
 
1. O’Keefe JH Jr, Vlietstra RE, Holmes DR: The transseptal approach for left heart catheterization. In: Holmes DR, Vlietstra RE, ed. The Practice of Interventional Cardiology. Philadelphia: FA Davis Publishing, 1988.
2. O'Keefe, JH Jr: Receptors and atherosclerosis. In: Gotto AM, ed. Atherosclerosis: A Decade in Perspective. New York: Medical Information Services, 1991.
3. O'Keefe, JH Jr: Primary angioplasty for acute myocardial infarction. In: Maresta A, ed. Advances in cardiology and cardiac surgery. Italy: Edizioni CELI del, 1991.
4. O’Keefe JH Jr, Hartzler GO: Summary of previous restenosis trials. In: Schwartz RS. ed. Coronary Restenosis. Blackwell Scientific Publications, 1992.
5. O’Keefe JH Jr, Hammill SC, Zolnick, MR, Steinhaus, DM, Vatterott, PJ: Electrocardiography Study Guide, Mayo Clinic Cardiology Review. Futura Publishing Company, Inc., 1994.
6. O’Keefe JH Jr, Ballantyne, CM, Kaplan, NM, Freed, MS: Cardiovascular Risk Reduction.  In: Safian RD, Freed, MS.  The Manual of Interventional Cardiology.  Physician’s Press, 2001
7. Bybee, KA, Das, S, O'Keefe, JH Jr: The Rationale and Indications for Angiotensin Receptor Blockers in Heart Failure.  Heart Failure Clinics, Volume 2, Number 1, January 2006. 
8. O'Keefe, JH Jr: Aggressive LDL reduction (of 50% or more) to physiologically normal is required to optimize cardiovascular prognosis. Merck Monograph January 2006 (for Cardiologists).
9. O’Keefe JH Jr, Pepine, CJ: New Frontiers in CVD risk management supporting early aggressive therapy.  Vascular Biology Working Group CME Monograph. February 2006, Volume 7, Number 2.
10. Park SY:  Breathe Better, Sleep Better: How Sleep Position Effects Your Health and Your Life.  Reviewed book.  November 2007.
11. Bell DHS:  Diet for Life.  Forward chapter and reviewed book.  December 2007.
 
BOOKS:
 
1. O’Keefe JH Jr, Hammill SC, Zolnick, MR, Steinhaus, DM, Vatterott, PJ: ECG Board Review and Study Guide.  Futura Publishing Company, Inc., copyright 1994.
2. O’Keefe JH Jr, Hammill SC, Freed, M: The Complete Guide to ECGs: A comprehensive study guide to improve ECG interpretation skills.  Physicians Press, Birmingham MI, 1997.
3. O’Keefe JH Jr, Hammill SC, Freed M, Pogwizd SM: The ECG Criteria and ACLS Handbook.  Physicians Press, Birmingham MI, 1998.
4. O’Keefe JH Jr, Hammill SC, Freed M, Pogwizd SM: The Complete Guide to ECGs: A Comprehensive Study Guide to Improve ECG Interpretation Skills 2nd Edition.  Physicians’ Press, Birmingham, MI, 2002.
5. O'Keefe JH Jr, Hammill SC, Freed M, Pogwizd SM: The ECG Criteria Book. Physicians’ Press, Birmingham, MI, 2002.
6. Califf RM, Kaplan NM, Ballantyne CM, Fuster V, Chatterjee K, Caplan LR, Goldszmidt AJ, Hammill SC, O'Keefe JH Jr, Freed MS: Common Pitfalls in Cardiology.  Physicians’ Press, Birmingham, MI, 2002.
7. Ballantyne CM, O'Keefe JH Jr, Gotto AM: Dyslipidemia Essentials.  Physician’s Press, Birmingham, MI, 2003.
8. O'Keefe JH Jr, Bell DS, Wyne K, Haffner SM: Diabetes Essentials, Physician’s Press, 150 Pages, Birmingham, MI, April 2004.  
9. O'Keefe JH Jr, O’Keefe J: The Forever Young Diet and Lifestyle. Andrews McMeel Universal, Kansas City, MO, November 2005.
10. O'Keefe JH Jr, Bell DS, Wyne K, Haffner SM: Diabetes Essentials, 3rd Edition, Physician’s Press, Birmingham, MI, 2008 October.
11. O'Keefe JH Jr, Hammill SC, Freed M, Pogwizd SM: The ECG Criteria Book. Physicians’ Press, Birmingham, MI, 2008 October.
12. Ballantyne CM, O’Keefe JH Jr, Gotto AM Jr: Dyslipidemia Essentials 2008, 3rd Edition.  Physicians’ Press, Royal Oak, MI, 2008 December.
13. O’Keefe JH Jr, Hammill SC, Freed, M: The Complete Guide to ECGs: A comprehensive study guide to improve ECG interpretation skills.  Physicians Press, Birmingham MI, 2010.  Versions in Italian, French, Chinese
14. O'Keefe JH Jr, Hammill SC, Freed M, Pogwizd SM: The ECG Criteria Book-2nd Edition-pocket version. Physicians’ Press, Birmingham, MI, 2010 September.  
 
GENERAL LITERATURE PUBLICATIONS:
 
1. O’Keefe JH Jr, Editor in Chief. “From The Heart” Publication from Cardiovascular Consultants. Circulation 120,000. Published three times per year 1996 to present.  Ten-time winner of Healthcare Advertising Awards National Competition.
2. O’Keefe JH Jr, Regular Contributor. “50 and Better” Magazine.
3. Brody, JE, O'Keefe, JH Jr: NY Times-Personal Health Section: Ancient Tool of Survival is Deadly for the Heart, May 21, 2002.
4. O’Keefe JH Jr, Abuissa, H: ACE inhibitors or ARBs for prevention of type 2 diabetes: a meta-analysis of randomized clinical trials. Medscape online April 21, 2005.  URL: http://www.medscape.com/viewarticle/052893.
5. O’Keefe JH Jr, Abuissa, H: ASCOT-BPLA: Calcium blocker/ACE inhibitor regimen superior to beta-blocker/diuretic regimen. Medscape online April 21, 2005. URL: http://www.medscape.com/viewarticle/052896.
6. O’Keefe JH Jr, Bybee KA, Lavie CJ:  Alcohol and cardiovascular health.  Medscape’s Monthly Top Cardiology Article. September 2007.  URL:  http://www.medscape.com/viewarticle/562474?sssdmh=dm1.306613&src=top10
7. Lee JH, O’Keefe JH Jr:  Here’s to your health: May you always drink lightly (How and why alcohol is a potent double-edged sword).  Cyberounds program for Albert Einstein College of Medicine, 2008.  http://www.cyberounds.com/. 
8. O’Keefe JH Jr, Contributor. Enhance Magazine.
 
PUBLICATIONS:
 
1. O’Keefe JH Jr, Hayes DL, Holmes DR Jr, Vlietstra RE: Importance and long-term utility of a multiparameter programmable pulse generator. Mayo Clin Proc. 59 (4): 239-242, 1984 April.
2. O’Keefe JH Jr, Vlietstra RE, Hanley PC, Seward JB: Revival of the transseptal approach for catheterization of the left atrium and ventricle. Mayo Clin Proc. 60 (11): 790-795, 1985 November.
3. O’Keefe JH, Kwong EM, Tancredi RG: Transgingival nitrate syncope. Letter to the Editor.  N Engl J Med. 315(16):1030, 1986 October 16.
4. O’Keefe JH Jr, Holmes DR Jr, Schaff HV, Sheedy PF 2nd, Edwards WD: Thromboembolic splenic infarction.  Mayo Clin Proc. 61(12):967-972, 1986 December. 
5. O’Keefe JH Jr, Owen RM, Bove AA: Influence of left ventricular mass on coronary artery cross-sectional area. Am J Cardiol. 59(15):1395-1397, 1987 June 1.
6. O’Keefe JH Jr, Vlietstra RE, Bailey KR, Holmes DR Jr: Natural history of candidates for balloon aortic valvuloplasty. Mayo Clin Proc. 62(11):986-991, 1987 November.
7. O’Keefe JH Jr, Lapeyre AC 3rd, Holmes DR Jr, Gibbonw RJ: Usefulness of early radionuclide angiography for identifying low-risk patients for late restenosis after percutaneous transluminal coronary angioplasty. Am J Cardiol. 61(1):51-54, 1988 January 1.
8. O’Keefe JH Jr, Reeder GS, Miller GA, Bailey KR, Holmes DR Jr: Safety and efficacy of percutaneous transluminal coronary angioplasty performed at time of diagnostic catheterization compared with that performed at other times. Am J Cardiol. 63(1):27-29, 1989 January 1.
9. O’Keefe JH Jr, Holmes DR Jr, Reeder GS, Bresnahan DR: A new approach for dilation of bifurcation stenoses: the dual probe technique. Mayo Clin Proc. 64(3): 277-281, 1989 March.
10. O’Keefe JH Jr, Hartzler GO: Restenosis after coronary angioplasty.  J Inv Car. 1(2):109-122, 1989 March.
11. O’Keefe JH Jr, Shub C, Rettke SR: Risk of noncardiac surgical procedures in patients with aortic stenosis. Mayo Clin Proc. 64(4):400-405, 1989 April.
12. O’Keefe JH Jr, Lavie CF, O’Keefe JO: Dietary prevention of coronary artery disease. How to help patients modify eating habits and reduce cholesterol. Postgrad Med. 85(6):243-50, 257-261, 1989 May 1. 
 
 
13. O’Keefe JH Jr, Zinsmeister AR, Gibbons RJ: Value of normal electrocardiographic findings in predicting resting left ventricular function in patients with chest pain and suspected coronary artery disease. Am J Med. 86(6 Pt 1):658-662, 1989 June.
14. O’Keefe JH Jr, Hartzler GO, Rutherford BD, McConahay DR, Johnson WL, Giorgi LV, Ligon RW: Left main coronary angioplasty: early and late results of 127 acute and elective procedures. Am J Cardiol. 64(3):144-147, 1989 July 15.
15. O’Keefe JH Jr, Rutherford BD, McConahay DR, Ligon RW, Johnson WL Jr, Giorgi LV, Crockett, JE, McCallister BD, Conn, RD, Gura, GM Jr, et al: Early and late results of coronary angioplasty without antecedent thrombolytic therapy for acute myocardial infarction. Am J Cardiol. 64(19):1221-1230, 1989 December 1.
16. O’Keefe, JH, Shub C, Rettke SR: Risk of noncardiac surgical procedures in patients with aortic stenosis.  Survey of Anesthesiology. 34(2):82, 1990 April.
17. Lavie CJ, O’Keefe JH Jr, Blonde L, Gau GT: High-density lipoprotein cholesterol. Recommendations for routine testing and treatment. Postgrad Med. 87(7):36-44, 47, 51, 1990 May 15.
18. Lavie CJ, O’Keefe JH Jr, Chesebro JH, Clements IP, Gibbons RJ: Prevention of late ventricular dilatation after acute myocardial infarction by successful thrombolytic reperfusion. Am J Cardiol. 66(1):31-36, 1990 Jul 1.  Erratum in: Am J Cardiol. 66(7):772, 1990 September 15.
19. O’Keefe JH Jr, Rutherford BD, McConahay DR, Johnson WL Jr, Giorgi LV, Ligon RW, Shimshak TM, Hartzler GO: Multivessel coronary angioplasty from 1980 to 1989: procedural results and long-term outcome. J Am Coll Cardiol. 16(5): 1097-1102, 1990 November 1.
20. Kahn JK, O’Keefe JH Jr, Rutherford BD, McConahay DR, Johnson WL, Giorgi LV, Shimshak TM, Ligon RW, Hartzler GO: Timing and mechanism of in-hospital and late death after primary coronary angioplasty during acute myocardial infarction. Am J Cardiol. 66:1045-1048, 1990 November 1.
21. O’Keefe JH Jr, Lavie CJ, Nishimura RA, Edwards WD: Degenerative aortic stenosis. One effect of the graying of America. Postgrad Med. 89(2):143-146,151-4, 1991 February 1. 
22. O’Keefe JH Jr, Giorgi LV, Hartzler GO, Good TH, Ligon RW, Webb DL, McCallister BD: Effects of diltiazem on complications and restenosis after coronary angioplasty. Am J Cardiol. 67(5):373-376, 1991 February 15.
23. Bedotto JB, Rutherford BD, McConahay DR, Johnson WL, Giorgi LV, Shimshak TM, O’Keefe JH Jr, Ligon RW, Hartzler GO: Results of multivessel percutaneous transluminal coronary angioplasty in persons aged 65 years and older. Am J Cardiol. 67(13):1051-1055, 1991 May 15.
24. O’Keefe JH Jr, Gernon C, McCallister BD, Ligon RW, Hartzler GO: Safety and cost effectiveness of combined coronary angiography and angioplasty. Am Heart J. 122(1 Pt 1):50-54, 1991 July.
25. O’Keefe JH Jr, Rutherford BD, McConahay DR, Johnson WL Jr, Giorgi LV, Shimshak TM, Ligon RW, McCallister BD, Hartzler GO: Myocardial salvage with direct coronary angioplasty for acute infarction. Am Heart J. 123(1):1-6, 1992 January.
26. Bateman TM, O’Keefe, JH Jr: Pharmacological (stress) perfusion scintigraphy: methods, advantages, and applications. Am J Card Imaging. 6(1):3-13; discussion 14-5, 1992 March. 
27. O’Keefe JH Jr, McCallister BD: Evolution of revascularization strategies for single-vessel coronary artery disease. Editorial. Mayo Clin Proc. 67(4):389-391, 1992 April.
28. O’Keefe JH Jr, McCallister BD, Bateman TM, Kuhnlein DL, Ligon RW, Hartzler GO: Ineffectiveness of colchicine for the prevention of restenosis after coronary angioplasty. J Am Coll Cardiol. 19(7):1597-1600, 1992 June.
29. O’Keefe JH Jr, Bateman TM, Silvestri R, Barnhart C: Safety and diagnostic accuracy of adenosine thallium-201 scintigraphy in patients unable to exercise and those with left bundle branch block. Am Heart J. 124(3):614-621, 1992 September.
30. Grines CL, Browne KF, Marco J, Rothbau D, Stone GE, O’Keefe JH Jr, Overlie P, Donohue B, Chelliah N, Timmis GC, Vlietstra RE, Strzelecki M, Puchrowicz-Ochocki S, O’Neill WW: A comparison of immediate angioplasty with thrombolytic therapy for acute myocardial infarction (PAMI). N Eng J Med. 328(10):673-679, 1993, March 11.
31. O’Keefe JH Jr, Allan, JJ, McCallister BD, McConahay DR, Vacek JL, Piehler JM, Ligon R, Hartzler GO: Angioplasty versus bypass surgery for multivessel coronary artery disease with left ventricular ejection fraction < or = 40%. Am J Cardiol. 71(11):897-901, 1993 April 15.
32. O’Keefe JH Jr, Bateman TM, Barnhart CS: Adenosine thallium-201 is superior to exercise thallium-201 for detecting coronary artery disease in patients with left bundle branch block. J Am Coll Cardiol. 21(6):1332-1338, 1993 May.
33. Bedotto JB, Kahn JK, Rutherford BD, McConahay DR, Giorgi LV, Johnson WL, O’Keefe JH Jr, Shimshak TM, Ligon RW, Hartzler GO: Failed direct coronary angioplasty for acute myocardial infarction: in-hospital outcome and predictors of death. J Am Coll Cardiol. 22(3):690-694, 1993 September.
34. O’Keefe JH Jr, Lavie CJ: Vitamin E and the risk of coronary disease. (Comment and Letter) N Engl J Med. 329(19):1424-1425, 1993 November 4.
35. O’Keefe JH Jr, Bailey WL, Rutherford BD, Hartzler GO: Primary angioplasty for acute myocardial infarction in 1,000 consecutive patients. Results in an unselected population and high-risk subgroups. Am J Cardiol. 72(19):107G-115G, 1993 December 16.
36. Bateman TM, Kolobrodov VV, Vasin AP, O’Keefe, JH Jr: Extended acquisition for minimizing attenuation artifact in SPECT cardiac perfusion imaging. J Nucl Med. 35(4):625-627, 1994 April.
37. O’Neill WW, Brodie BR, Inanhoe R, Knopf W, Taylor G, O’Keefe J, Grines CL, Weintraub R, Sickinger BG, Berdan LG: Primary coronary angioplasty for acute myocardial infarction (the Primary Angioplasty Registry). Am J Cardiol. 73(9):627-634, 1994 April 1.
38. Brodie BR, Grines CL, Ivanhoe R, Knopf W, Taylor G, O’Keefe JH Jr, Weintraub RA, Berdan LG, Tcheng JE, Woodlief LH, Califf RM, O’Neill WW: Six-month clinical and angiographic follow-up after direct angioplasty for acute myocardial infarction: final results from the primary angioplasty registry.  Circulation. 25:156-162, 1994 July.
39. O’Keefe JH Jr, Sutton MB, McCallister BD, Vacek JL, Piehler JM, Ligon RW, Hartzler GO: Coronary angioplasty versus bypass surgery in patients > 70 years old matched for ventricular function. J Am Coll Cardiol. 24(2):425-430, 1994 August.
40. Weyrens, FJ, Goldenberg, I, Mooney, JF, Holmes DR, O’Keefe JH Jr, Myler, RK, Shaw, R, Weintraub, W, Crowley, M, Kern, M, Nahhas, AT, Mooney, MR: Percutaneous transluminal coronary angioplasty in patients  90 years. Am J Cardiol. 74:397-398, 1994 August.
41. O’Keefe JH Jr, Lavie CJ Jr, McCallister BD: Insights into the pathogenesis and prevention of coronary artery disease. Mayo Clin Proc. 70(1):69-79, 1995 Jan. 
42. O’Keefe JH Jr, Grines CL, DeWood MA, Bateman TM, Christian TF, Gibbons RJ: Factors influencing myocardial salvage with primary angioplasty. J Nucl Cardiol. 2(1):35-41, 1995 January/February.
43. Stone, GW, Grines CL, Browne KF, Marco J, Rothbaum, D, O’Keefe JH Jr, Hartzler GO, Overlie P, Donohue B, Chelliah N, Timmis GC, Vlietstra, R, Strzelecki M, Puchrowicz-Ochocki, S, O’Neill, WW: Predictors of in-hospital and 6-month outcome after acute myocardial infarction in the reperfusion era: The Primary Angioplasty in Myocardial Infarction (PAMI) Trial. J Am Coll Cardiol. 25:370-377, 1995 February.
44. Lavie CJ, O’Keefe JH Jr, Mehra MR, Milani RV:  Potential role of antioxidants in the primary and secondary prevention of atheroslcerosis in the elderly.  Cardiol Elderly. 3(1): 21-25, 1995 February.
45. O’Keefe, JH Jr, Nguyen T, Nelson J, O’Keefe JO, Miles JM: Potential beneficial effects of monounsaturated and polyunsaturated fats in elderly patients with or at risk of coronary artery disease.  Cardiol Elderly. 3(1): 5-10, 1995 February.
46. O’Keefe JH Jr, Bateman TM, Handlin LR, Barnhart CS: Four- versus 6-minute infusion protocol for adenosine thallium-201 single photon emission computed tomography imaging. Am Heart J. 129(3):482-487, 1995 March.
47. O’Keefe JH Jr, Sayed-Taha K, Gibson W, Christian TF, Bateman TM, Gibbons RJ: Do patients with left circumflex coronary artery-related acute myocardial infarction without ST-segment elevation benefit from reperfusion therapy? Am J Cardiol. 75(10):718-720, 1995 April 1.
48. O’Keefe JH Jr, Barnhart CS, Bateman TM: Comparison of stress echocardiography and stress myocardial perfusion scintigraphy for diagnosing coronary artery disease and assessing its severity. Am J Cardiol. 75(11):25D-34D, 1995 April 13. 
49. Stone GW, Grines CL, Browne KF, Marco J, Rothbaum D, O’Keefe JH Jr, Hartzler GO, Overlie P, Donohue B, Chelliah N: Comparison of in-hospital outcome in men versus women treated by either thrombolytic therapy or primary coronary angioplasty for acute myocardial infarction.  Am J Cardiol. 75(15):987-992, 1995 May 15.
50. Bateman TM, O’Keefe JH Jr, Dong VM, Barnhart C, Ligon RW: Coronary angiographic rates after stress single-photon emission computed tomographic scintigraphy. J Nucl Cardiol. 2(3):217-223, 1995 May-June.
51. O’Connor MK, Gibbons RJ, Juni JE, O’Keefe JH Jr, Ali A: Quantitative myocardial SPECT for infarct sizing: feasibility of a multicenter trial evaluated using a cardiac phantom.  J Nucl Med. 36(6):1130-1136, 1995 June.
52. Stone GW, Grines CL, Browne KF, Marco J, Rothbaum D, O’Keefe JH Jr, Hartzler GO, Overlie P, Donohue B, Chelliah N: Implications of recurrent ischemia after reperfusion therapy in acute myocardial infarction: a comparison of thrombolytic therapy and primary angioplasty. J Am Coll Cardiol. 26(1):66-72, 1995 July.
53. Mark DB, O’Neill WW, Brodie B, Ivanhoe R, Knopf W, Taylor G, O’Keefe JH Jr, Grines CL, Davidson-Ray L, Knight JD: Baseline and 6-month costs of primary angioplasty therapy for acute myocardial infarction: results from the primary angioplasty registry. J Am Coll Cardiol. 26(3):688-695, 1995 September.
54. O’Keefe JH Jr, Harris WS, Nelson J, Windsor SL: Effects of pravastatin with niacin or magnesium on lipid levels and postprandial lipemia. Am J Cardiol. 76(7):480-484, 1995 September 1.
55. O’Keefe JH Jr, Batemen TM, Lavie CJ Jr: Are invasive procedures...overused in angina patients? These cardiologists say no. Article and Review. Postgrad Med. 98(3):124-128, 134-135, 140-142, 1995 September.
56. O’Keefe JH Jr, Nelson J, Harris WS: Lifestyle change for coronary artery disease. What to tell patients. Article and Review. Postgrad Med. 99(2):89-106, 1996 February. 
57. O’Keefe JH Jr, McGraw J, Carter LF: Current indications for coronary angioplasty and bypass graft surgery. Integ Med. 17-42, 1996 April.
58. O’Keefe JH Jr, Stone GW, McCallister BD Jr, Massex C, Ligon R, Kacich RL, Kahn J, Cavero PG, Hartzler GO, McCallister BD: Lovastatin plus probucol for prevention of restenosis after percutaneous transluminal coronary angioplasty. Am J Cardiol. 77(8):649-652, 1996 March 15.
59. Stone GW, Grines CL, Browne KF, Marco J, Rothbaum D, O’Keefe JH Jr, Hartzler GO, Overlie P, Donohue B, Chelliah N, Vlietstra R, Puchrowicz-Ochocki S, O’Neill WW: Influence of acute myocardial infarction location on in-hospital and late outcome after primary percutaneous transluminal coronary angioplasty versus tissue plasminogen activator therapy. Am J Cardiol. 78(1):19-25, 1996, July 1.
60. Lavie CJ, Milani RV, O’Keefe JH Jr: Update on new coronary risk factors. Editorial. Chest. 110(3):583-584, 1996 September.
61. Laster SB, O’Keefe JH Jr, Gibbons RJ: Incidence and importance of thrombolysis in myocardial infarction grade 3 flow after primary percutaneous transluminal coronary angioplasty for acute myocardial infarction. Am J Cardiol. 78(6):623-626, 1996 September 15.
62. O’Keefe JH Jr, Conn RD, Lavie CJ, Bateman TM: The new paradigm for coronary artery disease: altering risk factors, atherosclerotic plaques, and clinical prognosis. Mayo Clin Proc. 71(10):957-965, 1996 October. 
63. O’Keefe JH Jr, Grines CL, DeWood MA, Schaer GL, Browne K, Magorien RD, Kalbfleisch JM, Fletcher WO Jr, Bateman TM, Gibbons RJ: Poloxamer-188 as an adjunct to primary percutaneous transluminal coronary angioplasty for acute myocardial infarction. Am J Cardiol. 78(7):747-750, 1996 October 1.
64. Stephan WJ, O’Keefe JH Jr, Piehler JM, McCallister BD, Dahiya RS, Shimshak TM, Ligon RW, Hartzler GO: Coronary angioplasty versus repeat coronary artery bypass grafting for patients with previous bypass surgery. J Am Coll Cardiol. 28(5):1140-1146, 1996 November 1.
65. Bateman TM, O’Keefe JH Jr, Williams ME: Incremental value of myocardial perfusion scintigraphy in prognosis and outcomes of patients with coronary artery disease. Curr Opin Cardiol. 11(6):613-620, 1996 November. 
 
 
66. Stone, GW, Grines CL, Browne KF, Marco J, Rothbaum, D, O’Keefe JH Jr, Hartzler GO, Overlie P, Donohue B, Chelliah N, Vlietstra, R, Puchrowica-Ochocki, S, O’Neill, WW: Outcome of different reperfusion strategies in patients with former contraindications to thrombolytic therapy: a comparison of primary angioplasty and tissue plasminogen activator. Primary Angioplasty in Myocardial Infarction (PAMI) Investigators. Cathet Cardiovasc Diagn. 39(4):333-339, 1996 December.
67. O’Keefe JH Jr, Kim SC, Hall RR, Cochran VC, Lawhorn SL, McCallister BD: Estrogen replacement therapy after coronary angioplasty in women. J Am Coll Cardiol. 29(1):1-5, 1997 January.
68. Bateman TM, O’Keefe JH Jr, Williams ME: Design and implementation of a nuclear cardiology testing facility in a private-practice cardiology office setting. J Nucl Cardiol. 4(2 Pt 1):156-163, 1997 March/April.
69. Magalski A, O’Keefe, JH Jr: Thrombolysis or primary angioplasty for acute myocardial infarction? N Engl J Med. 336(15):1101-1102; author reply 1102-1103, 1997 April 10.
70. Stone GW, Grines CL, Rothbaum D, Browne KF, O’Keefe, JH Jr, Overlie PA, Donohue BC, Chelliah N, Vlietstra R, Catlin T, O’Neill WW:  Analysis of the relative costs and effectiveness of primary angioplasty versus tissue-type plasminogen activator: the Primary Angioplasty in Myocardial Infarction (PAMI) trial.  The PAMI Trial Investigators.  J Am Coll Cardiol.  29(5):901-907, 1997 April.
71. O’Keefe JH Jr, Harris WS: Nicotinic acid - the underused ally in the fight against coronary disease. J Cardiovasc Risk. 4(3):161-163, 1997 June. 
72. Strychacaz CP, Vacek JL, O’Keefe JH Jr, Willis FN, Hileman JW, Hewitt J, Breytspraak LM, Rinck CM: Predicting distress in married men and women heart revascularization patients: coping strategies and self-efficacy. Circulation. 96(8S), 279-281, 1997 October 21.
73. Chareonthaitawee, P, Christian, TF, O’Connor, MK, Berger, PB, Higano, ST, O’Keefe JH Jr, Spain MG, Grines CL, Gibbons RJ: Noninvasive prediction of residual blood flow within the risk area during acute myocardial infarction: a multicenter validation study of patients undergoing direct coronary angioplasty. Am Heart J. 134(4):639-646, 1997 October.
74. Gum PA, O’Keefe JH Jr, Borkon AM, Spertus JA, Bateman TM, McGraw JP, Sherwani K, Vacek J, McCallister BD: Bypass surgery versus coronary angioplasty for revascularization of treated diabetic patients. Circulation. 96(9 Suppl):II-7-10, 1997 November 4.
75. O’Keefe JH Jr, Bateman TM, Ligon RW, Case J, Cullom J, Barnhart C, Spertus J: Outcome of medical versus invasive treatment strategies for non-high-risk ischemic heart disease. J Nucl Cardiol. 5(1):28-33, 1998 January/February.
76. Christian TF, O’Keefe JH Jr, DeWood MA, Spain MG, Grines CL, Berger PB, Gibbons RJ: Intercenter variability in outcome for patients treated with direct coronary angioplasty during acute myocardial infarction. Am Heart J. 135(2 Pt 1):310-317, 1998 February.
77. Miller TD, Hodge DO, Sutton JM, Grines CL, O’Keefe JH Jr, DeWood MA, Okada RD, Fletcher WO Jr, Gibbons RJ: Usefulness of technetium-99m sestamibi infarct size in predicting posthospital mortality following acute myocardial infarction. Am J Cardiol. 81(12):1491-1493, 1998 June 15.
78. O’Keefe JH Jr, Blackstone EH, Sergeant P, McCallister BD: The optimal mode of coronary revascularization for diabetics. A risk-adjusted long-term study comparing coronary angioplasty and coronary bypass surgery. Eur Heart J. 19(11):1696-1703, 1998 November.
79. O’Keefe JH Jr, Miles JM, Harris WH, Moe RM, McCallister BD: Improving the adverse cardiovascular prognosis of type 2 diabetes. Mayo Clin Proc. 74(2):171-180, 1999 February. 
80. Alaswad K, O’Keefe JH Jr, Moe RM: Combination drug therapy for dyslipidemia.  Curr Atheroscler Rep. 1(1):44-49, 1999 July.
81. O’Keefe JH Jr, McCallister BD, Blackstone EH: Sulfonylurea drugs and cardiovascular mortality. Letter to the Editor. J Am Coll Cardio. 34(3):958, 1999 September.
82. Harris WS, Gowda M, Kolb JW, Strychacz CP, Vacek JL, Jones PG, Forker A, O’Keefe JH Jr, McCallister BD:  A randomized, controlled trial of the effects of remote, intercessory prayer on outcomes in patients admitted to the coronary care unit.  Arch Intern Med. 159:2273-2278, 1999 October 25.
83. O’Keefe JH Jr, Bateman TM, Gibbong RJ: Exercise echocardiography vs exercise SPECT testing.  Letter to the Editor. J Am Med Assoc. 282(17):1621-1622, 1999 November 3.
84. O’Keefe JH Jr, Kreamer TR, Jones PG, Vacek JL, Gorton ME, Muehlebach GF, Rutherford BD, McCallister BD: Isolated left anterior descending coronary artery disease: percutaneous transluminal coronary angioplasty versus stenting versus left internal mammary artery bypass grafting.  Circulation. 100(suppl II):II-114-II-118), 1999 November 9.
85. Harris WS, Gowda M, Kolb JW, Strychacz CP, Vacek JL, Jones PG, Forker A, O’Keefe JH Jr, McCallister BD: A randomized, controlled trial of the effects of remote, intercessory prayer on outcomes in patients admitted to the coronary care unit. Arch Intern Med. 159(19):2273-2278, 1999 October 25. Erratum in: Arch Intern Med. 160(12):1878, 2000 June 26.
86. O’Keefe JH Jr, Bateman TM, Gibbons RJ:  Exercise echocardiography vs exercise SPECT testing. Letter to Editor.  JAMA, 282(17):1621-1623, 1999 November 3.
87. O’Keefe JH Jr, Kreamer TR, Jones PG, Vacek JL, Gorton ME, Muehlebach GF, Rutherford BD, McCallister BD:  Isolated left anterior descending coronary artery disease: percutaneous transluminal coronary angioplasty versus left internal mammary artery bypass grafting.  Circulation. 100(19S):II14-18, 1999 November 9.
88. O’Keefe JH Jr, Magalski A, Stevens TL, Bresnahan DR Jr, Alaswad K, Krueger SK, Bateman TM: Predictors of improvement in left ventricular ejection fraction with carvedilol for congestive heart failure. J Nucl Cardiol. 7(1):3-7, 2000 January/February.
89. O’Keefe JH Jr, Harris WS: Omega-3 fatty acids: time for clinical implementation? Am J Cardiol. 85(10):1239-1241, 2000 May 15.
90. O’Keefe JH Jr, Harris WS: From Inuit to implementation: omega-3 fatty acids come of age. Mayo Clin Proc. 75(6):607-614, 2000 June. 
 
 
91. Harris WS, Gowda M, Kolb JW, Strychacz CP, Vacek JL, Jones PG, Forker A, O’Keefe JH Jr, McCallister BD: God, Prayer, and Coronary Care Unit Outcomes: Faith vs Works? Arch Intern Med. Reply. 160(12):1877-1878, 2000 June 26.
92. Bybee, KA, O’Keefe JH Jr, Harris, WS, Garg, S, George, SJ, Bateman TM: Lipid risk factor correlates of ischemic heart disease as diagnosed by myocardial perfusion scintigraphy. Prev Cardiol. 2000 Fall;3(4):33-39.
93. O’Keefe JH Jr, Gibbson RJ: Left circumflex occlusion--underrecognized and undertreated. J Thromb Thrombolysis. 10(3):221-225, 2000 December. 
94. O’Keefe JH Jr, Wetzel M, Moe RR, Brensnahan K, Lavie CJ: Should an angiotensin-converting enzyme inhibitor be standard therapy for patients with atherosclerotic disease? J Am Coll Cardiol. 37(1):1-8, 2001January. 
95. Harris WS, O’Keefe JH Jr: Cardioprotective effects of omega-3 fatty acids. Nutr Clin Pract. 16(1):6-12, 2001 February.
96. Harris WS, Gowda M, Kolb JW, Strychacz CP, Vacek JL, Jones PG, Forker A, O’Keefe JH Jr, McCallister BD: A randomized, controlled trial of the effects of remote, intercessory prayer on outcomes in patients admitted to the coronary care unit. Literature Update from 1999. J Cardiopulm Rehabil. 21(2):118-122, 2001 March/April.
97. Goldstein BJ, O’Keefe JH Jr, Safford MM, Unger J: Controlling Type 2 Diabetes. Medical Crossfire. 3(6):33-43, 2001 June.
98. Spertus JA, Jones PG, Coen M, Garg M, Bliven B, O’Keefe JH Jr, March RJ, Horvath K: Transmyocardial CO2 laser revascularization improves symptoms, function, and quality of life: 12-month results from a randomized controlled trial. Am J Med. 111(5):341-348, 2001 October 1.
99. Curtis BM, O’Keefe JH Jr: Autonomic tone as a cardiovascular risk factor: the dangers of chronic fight or flight. Review. Mayo Clin Proc. 77(1):45-54, 2002 January.
100. Alaswad K, Lavie CJ, Milani RV, O’Keefe JH Jr: Fish oil in cardiovascular prevention. Ochsner J. 4(2):83-91, 2002 Spring.
101. O’Keefe JH Jr, Curtis BM: Autonomic tone and benefits of cardiac rehabilitation programs.  Letters to the Editor. Mayo Clin Proc. 77(4), 399-400, 2002 April.
102. O’Keefe JH Jr, Plapp FV: Chronic sympathetic activation. Letters to the Editor. Mayo Clin Proc. 77(7), 735-736, 2002 July.
103. Curtis BM, O’Keefe JH Jr: Understanding the Mediterranean diet. Could this be the new "gold standard" for heart disease prevention? Postgrad Med. 112(2):35-38, 41-45, 2002 August. 
104. O’Keefe JH Jr, Lurk JT, Kahatapitiya RC, Haskin JA: The renin-angiotensin-aldosterone system as a target in coronary disease. Curr Atheroscler Rep. 5(2):124-130, 2003 March. 
105. Harris WS, O’Keefe JH Jr:  Preventive use of N-3 fatty acids. Circulation. 107(14):1834-1836, 2003 April 15.
106. Harris WS, O’Keefe JH Jr:  Preventive use of N-3 fatty acids. Circulation. 108(19):e139; author reply e139, 2003 November 11.
 
 
 
107. Marso SP, Gowda M, O’Keefe JH Jr, Coen MM, McCallister BD, Giorgi LV, Huber KC, Laster SB, Johnson WL, Rutherford BD: Improving in-hospital mortality in the setting of an increasing risk profile among patients undergoing catheter-based reperfusion for an acute myocardial infarction without cardiogenic shock.  J Invasive Cardiol. 15(12):711-716, 2003 December.
108. Moser KW, O’Keefe JH Jr, Bateman TM, McGhie AI: Coronary calcium screening in asymptomatic patients as a guide to risk factor modification and stress myocardial perfusion imaging. J Nucl Cardiol. 10(6):590-598, 2003 November/December.
109. O’Keefe JH Jr, Cordain L: Cardiovascular disease resulting from a diet and lifestyle at odds with our Paleolithic genome: how to become a 21st-century hunter-gatherer.  Mayo Clin Proc. 79(1):101-108, 2004 January. 
110. O’Keefe JH Jr, Poston WS, Haddock CK, Moe RM, Harris W: Psychosocial stress and cardiovascular disease: how to heal a broken heart. Compr Ther. 30(1):37-43, 2004 March. 
111. Moser KW, Bateman TM, O’Keefe JH Jr, McGhie AI: Interscan variability of coronary artery calcium quantification using an electrocardiographically pulsed spiral computed tomographic protocol. Am J Cardiol. 93(9):1153-1135, 2004 May 1.
112. Vaglio J Jr, Conard M, Poston WS, O’Keefe JH Jr, Haddock CK, House J, Spertus JA: Testing the performance of the ENRICHD social support instrument in cardiac patients.  Health Qual Life Outcomes. 2:24, 2004 May 13.
113. O’Keefe JH Jr, Cordain L, Harris WM, Moe RM, Vogel R: Optimal low-density lipoprotein is 50 to 70 mg/dl: lower is better and physiologically normal. J Am Coll Cardiol.  2;43(11):2142-2146, 2004 June. 
114. O’Keefe JH Jr, Captain BK, Jones PG, Harris WS: Atorvastatin reduces remnant lipoproteins and small, dense low-density lipoproteins regardless of the baseline lipid pattern. Prev Cardiol. 7(4):154-160, 2004 Fall/November.
115. O’Keefe JH Jr: Have recent statin trial findings affected the National Cholesterol Education Program guidelines? Nat Clin Pract Cardiovasc Med. 1(2):76-77, 2004 December.
116. Cordain L, Eaton SB, Sebastian A, Mann N, Lindeberg S, Watkins BA, O’Keefe JH Jr, Brand-Miller J: Origins and evolution of the Western diet: health implications for the 21st century. Am J Clin Nutr. 81(2):341-354, 2005 February. 
117. O’Keefe JH Jr, Abuissa H, Jones PG, Thompson RC, Batemen TM, McGhie AI, Ramza BM, Steinhaus DM: Effect of chronic right ventricular apical pacing on left ventricular function. Am J Cardiol. 95(6):771-773, 2005 March 15.
118. O’Keefe JH Jr, Cordain L, Harris WM, Moe RM, Vogel R: Optimal lipids, statins, and dementia: Reply. J Am Coll Cardiol.  45:964-965, 2005 March. 
119. Abuissa H, O’Keefe JH Jr, Harris W, Lavie CJ: Autonomic function, omega-3, and cardiovascular risk. Editorial.  Chest. 127(4):1088-1091, 2005 April.
120. Harris WS, O’Keefe, JH Jr: Cardiology Q & A: matters of the heart. Consultant. 45(6):620-624, 2005 May.
121. Spertus J, Decker C, Woodman C, House J, Jones P, O’Keefe JH Jr, Borkon AM:  Effect of difficulty affording health care on health status after coronary revascularization.  Circulation. 111:2572-2578, 2005 May 24.
122. O’Keefe JH, Cordain L, Harris WH, Moe RM, Vogel R:  Correspondence: Letter to the Editor, Optimal lipids, statins, and dementia.  J Am Coll Cardiol. 45(10):1732, 2005, May.
123. Abuissa H, Bell DS, O’Keefe JH Jr: Strategies to prevent type 2 diabetes. Curr Med Res Opin.  21(7):1107-1114, 2005 July. 
124. Thompson RC, McGhie AI, Moser KW, O’Keefe JH Jr, Stevens TL, House J, Fritsch N, Bateman TM: Clinical utility of coronary calcium scoring after nonischemic myocardial perfusion imaging. J Nucl Cardiol. 12(4):392-400, 2005 July/August.
125. Conaway DG, O’Keefe JH Jr, Reid KJ, Spertus J: Frequency of undiagnosed diabetes mellitus in patients with acute coronary syndrome. Am J Cardiol. 96(3):363-365, 2005 August 1.
126. Cordain L, Eaton SB, Sebastian A, Mann N, Lindeberg S, Watkins BA, O’Keefe JH Jr, Brand-Miller J: Origins and evolution of the Western diet: health implications for the 21st century. Reply to Editor. Am J Clin Nutr. 82(2):483-484, 2005 August. 
127. Abuissa H, O’Keefe JH Jr, Cordain L:  Realigning our 21st century diet and lifestyle with our hunter-gatherer genetic identity.  Dir in Psy. 25SR:1-11, 2005.
128. Abuissa H, Jones PG, Marsco SP, O’Keefe JH Jr: Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers for prevention of type 2 diabetes: a meta-analysis of randomized clinical trials. J Am Coll Cardiol. 46(5):821-826, 2005 September 6.
129. Bybee KA, Das S, O’Keefe JH Jr:  The rationale and indications for angiotensin receptor blockers in heart failure. Heart Fail Clin. 2(1):81-88, 2006 Jan.
130. Das S, O’Keefe JH Jr: Behavioral cardiology: recognizing and addressing the profound impact of psychosocial stress on cardiovascular health. Curr Atheroscler Rep.  8(2):111-118, 2006 March.
131. Abuissa H, Lavie CJ, Spertus J, O’Keefe JH Jr: Personal Health Habits of American Cardiologists.  Am J Cardiol. 97(7):1093-1096, 2006 April 1.
132. O’Keefe JH Jr, Abuissa H, Sastre A, Steinhaus DM, Harris WS: Effects of omega-3 fatty acids on resting heart rate, heart rate recovery after exercise, and heart rate variability in men with healed myocardial infarctions and depressed ejection variability fractions. Am J Cardiol. 97(8):1127-1130, Epub 2006 Mar 3, 2006 April 15. 
133. O’Keefe JH Jr, Cordain L, Jones PG, Abuissa H: Coronary artery disease prognosis and C-reactive protein levels improve in proportion to percent lowering of low-density lipoprotein.  Am J Cardiol. 98(1):135-139. Epub 2006 May 9, 2006 July 1.
134. Conaway DG, O’Keefe JH Jr:  Frequency of undiagnosed and untreated diabetes mellitus in patients with acute coronary syndromes. Expert Rev Cardiovasc Ther. 4(4):503-507, 2006 July.
135. Green Conway DL, Enriquez JR, Barberena JE, Jones PG, O’Keefe JH Jr, Spertus JA:  Assessment of and physician response to glycemic control in diabetic patients with an acute coronary syndrome.  Am Heart J. 152:1022-1027, 2006 December.
 
 
136. Boden WE, O’Rourke RA, Teo KK, Ch B, Hartigan PM, Maron DJ, Kostuk WJ, Knudtson M, Dada M, Casperson P, Harris CL, Chaitman BR, Shaw L, Gosselin G, Nawaz S, Title LM, Gau G, Blaustein AS, Booth DC, Bates ER, Spertus JA, Berman DS, Mancini GBJ, Weintraub WS, for the COURAGE Trial Research Group, O’Keefe JH - PI for MAHI site:  Optimal medical therapy with or without PCI for stable coronary disease.  NEJM. 356(15):1503-1516, 2007 April.
137. Lavie CJ, Milani RV, O’Keefe JH: Statin wars – Emphasis on potency versus event reduction and safety? Mayo Clin Proc. 82:539-542, 2007 May. 
138. O’Keefe JH Jr, Bell DSH: The postprandial hyperglycemia/hyperlipidemia (postprandial dysmetabolism) is a cardiovascular risk factor.  Am J Cardiol 100:899-904, 2007 September.   
139. O’Keefe JH Jr, Bybee KA, Lavie CJ:  Alcohol and cardiovascular health: The razor-sharp double-edged sword.  J Am Coll Cardiol 7;50:1009-1014, 2007 September.  
140. Bell DSH, O’Keefe JH Jr:  White cell count and mortality in the Baltimore Longitudinal Study of Aging.  Letter to the Editor.  J Am Coll Cardiol; 50:1810-1811, 2007 October 30.
141. O’Keefe JH Jr, Gheewala NM, O’Keefe JO:  Dietary strategies for improving postprandial glucose, lipids, inflammation and cardiovascular health.  J Am Coll Cardiol; 22;51(3):249-255, 2008 January.
142. Bell DS, O’Keefe JH Jr, Jellinger P:  Postprandial dysmetabolism: the missing link between diabetes and cardiovascular events?  Endocr Pract; 14(1):112-124, 2008 January/February.
143. Shaw LJ, Berman DS, Blumenthal RS, Budoff MJ, Faber TL, Goraya T, Halliburton SS, Hecht H, Kiat H, Koenig W, Malik S, Merhige M, Nasir K, Min JK, O’Keefe JH, Polk DM, et al:  Clinical imaging for prevention: directed strategies for improved detection of presymptomatic patients with undetected atherosclerosis – Part 1: Clinical imaging for prevention.  J Nucl Cardio. 15(1):e6-e19. 2008 January.
144. O’Keefe JH Jr, Lee JH:  Cardiac rehab in the quest for a happier and healthier heart.  South Med J; 101(3):225-226, 2008 March.
145. Lee JH, O’Keefe JH Jr, Lavie CJ, Marchioli R, Harris WS:  Omega-3 fatty acids for cardioprotection: Optimal dosage and DHA/EPA Ratio.  Mayo Clin Proc; 83(3):324-332, 2008 March.
146. Bybee KA, Lee JH, O’Keefe JH Jr:  Cumulative clinical data on atorvastatin for reducing cardiovascular events: the clinical impact of atorvastatin.  Curr Med Res and Opin; Epub 2008 March 20, 24(4):1217-1229, 2008 April. 
147. O’Keefe JH:  Nutrition 101:  Physicians can no longer ignore the healing power of diet and nutritional supplements.  Expert Rev Cardiovas Ther. 6(5):593-596, 2008 June.
148. O’Keefe JH Jr, Lee JH, Marchioli R, Lavie CJ, Harris WS:  Are all fish equally close to the heart?  Mayo Clin Proc; 83(6):723-730, 2008 June.
149. O’Keefe JH Jr, Abuissa H, Zarich S, Felicetta J, Patni R, Chu T, Solomon H, Pitt B:  Eplerenone improves prognosis in post-myocardial infarction diabetic patients with heart failure: results from EPHESUS.  Diabet Obes Metab.  2007 May 8, Epub ahead of print, 10(6):492-497, 2008 June.
150. Artham SM, Lavie CJ, Milani RV, Anand RG, O’Keefe JH, Ventura HO: Fish oil in primary and secondary cardiovascular prevention.  The Ochsner J. 8(2):49-60. 2008 June.
151. Lee JH, Abuannadi M, Jones PG, Bateman T, Thompson R, O’Keefe JH:  Dobutamine-induced chest pain does not predict ischemic findings on myocardial perfusion imaging.  J Nucl Cardiol; 15(4):526-529. Epub 2008 April 16, 2008 July-August.
152. Lavie CJ, Milani RV, O’Keefe JH:  The Russert Impact: A golden opportunity to promote primary coronary prevention.  The Ochsner J. 8(3):104-109. 2008 July.
153. O’Keefe JH, Bybee KA, Lavie CJ:  Intensive lipid intervention in the post-ENHANCE era.  Mayo Clin Proc; 83(8):867-869. 2008 August.
154. Weintraub WS, Spertus JA, Kolm P, Maron DJ, Zhang Z, Jurkovitz C, Zhang W, Hartigan PM, Lewis C, Veledar E, Bowen J, Dunbar SB, et al, COURAGE Trial Research Group, Mancini GB, O’Keefe JH - PI for MAHI site:  Effect of PCI on quality of life in patients with stable coronary disease.  NEJM. 359(7):677-687, 2008 August. 
155. Bell DS, O’Keefe JH:  Use of alternative thresholds defining insulin resistance to predict incident type 2 diabetes mellitus and cardiovascular disease.  Letter to the Editor. Circulation. 118(11):e156. 2008 September.
156. Bypass Angioplasty Revascularization Investigation 2 Study Group: Baseline characteristics of patients with diabetes and coronary artery disease enrolled in the Bypass Angioplasty Investigative 2 Diabetes (BARI 2D) Trial.  Am Heart J. 156(3):528-536, 536.e1-5. Epub 2008, July 31, 2008 September.  PI for MAHI site.
157. Das S, O’Keefe JH:  Behavioral cardiology: recognizing and addressing the profound impact of psychosocial stress on cardiovascular health.  Curr Hyptertens Rep. 10(5):374-81. 2008 October.
158. O’Keefe JH:  The essentials of diet and supplements for improving cardiovascular health.  Prim Care Cardiovasc J. 1(3):134-138, 2008 November.
159. Lee JH, Jones P, Bybee KA, O’Keefe JH:  Longer course of varenicline therapy improves smoking cessation.  Prev Cardio. 11(4):210-214, 2008 Fall/November.
160. Carter M, O’Keefe JH, Becker DJ, Gordon RY, Gordon J:  Is red yeast rice a suitable alternative for statins?  Letter to the Editor.  Mayo Clinic Proc, 83(11):1294. 2008 November.
161. O’Keefe JH, Bybee KA, Lavie CJ:  Is carotid intima-media thickness a reliable clinical predictor?  Letter to the Editor. Mayo Clinic Proc, 83(11):1299-1300. 2008 November.
162. Lee JH, Ngengwe R, Jones P, Tang F, O’Keefe JH:  Erectile dysfunction: Strongly associated with coronary calcium, a coronary artery disease risk equivalent?  J Nucl Cardiol. 15(6):800-803, 2008 November.
163. Abuissa H, O’Keefe JH:  The role of renin-angiotensin-aldosterone system-based therapy in diabetes prevention and cardiovascular and renal protection.  Diabetes Obes Metab. Epub 2008 May. 10(12):1157-1166. 2008 December. 
164. Lee JH, O’Keefe JH, Bell D, Hensrud DD, Holick MF:  Vitamin D deficiency: An important, common, and easily treatable cardiovascular risk factor?  J Am Coll Cardiol. 22;52(24):1949-1956, 2008 December.
 
165. Pop-Busui R, Lu J, Lopez N, Jones TL; BARI 2D Investigators: Prevalance of diabetic peripheral neuropathy and relation to glycemic control therapies at baseline in the BARI 2D cohort.  J Peripher Nerv Syst. 14(1):1-13. 2009 March.  PI for MAHI site.
166. Selden MA, Helzberg JH, Waeckerle JF, Browne JE, Brewer JH, Monaco ME, Tang F, O’Keefe JH:  Cardio-metabolic abnormalities in current national football league players.  Am J Cardiol;103(7):969-971. 2009 April.
167. O’Keefe JH, Carter MD, Lavie CJ, Bell DSH:  The gravity of JUPITER (Justification for the Use of Statins in Primary Prevention: an Intervention Trial Evaluating Rosuvastatin).  Postgrad Med;121(3):113-118, 2009 May.  
168. Bell DSH, O’Keefe JH:  Metabolic syndrome and post-operative atrial fibrillation (POAF).  Eur Heart J Advance Access published on April 17, 2009, DOI: 10.1093/eruheartj/ehp167. 2009 April.  Eur Heart J;30(10):1167-1168, 2009 May.
169. Lavie CJ, O’Keefe JH, Milani RV, Ventura HO, Mehra MR:  New data on the clinical impact of exercise training, fish oils, and statins in heart failure.  Phys Sports Med:2(37):22-28, 2009 June.
170. BARI 2D Study Group, Frye RL, August P, Brooks MM, Hardison RM, Kelsey SF, MacGregor JM, Orchard TJ, Chaitman BR, Genuth SM, Goldberg SH, Hlatky MA, Jones, TJ, Molitch ME, Nesto RW, Sobel BE: A randomized trial of therapies for type 2 diabetes and coronary artery disease.  NEJM 360(24):2503-2515.  2009 June.  Epub 2009, June 7, PI for MAHI site.
171. Conn RD, O’Keefe JH:  Cardiac physical diagnosis in the digital age: an important but increasingly neglected skill.  Am J Cardiol; 104(4):590-595. 2009 August 15.
172. O’Keefe JH, Carter MD, Lavie CJ: Primary and secondary cardiovascular prevention: A practical evidence-based approach.  Mayo Clin Proc;84(8):741-757. 2009 August.
173. Selden MA, Helzberg JH, Waeckerle JF, Browne JE, Brewer JH, Monaco ME, Tang F, O’Keefe JH:  Elevated alanine aminotransferase in current National Football League players: Correlation with cardio-metabolic syndrome markers, obesity, and insulin resistance.  S Med J 102(10):1003-1006.  2009 October.
174. Abuissa H, O’Keefe JH, Bybee KA:  Statins as anti-arrhythmics: A systematic review Part I and II: Effects on risk of atrial and ventricular arrhythmias.  Clin Cardiol; 32(10):544-552. 2009 October.    
175. Bell DSH, O’Keefe JH:  Rediscovering bile acid sequestrants. Epub ahead of print. 2009 September. Diabetes Obes Metab, 11(12):1114-1121. 2009 December. 
176. Lee JH, O’Keefe JH, Lavie CJ, Harris WS:  Omega-3 fatty acids: cardiovascular benefits, sources and sustainability. Epub ahead of print 2009 Oct.  Nat Rev Cardiol. 6(12):753-758.  2009 December.
177. Lavie CJ, Milani RV, Verma A, O’Keefe JH:  C-reactive protein and cardiovascular disease – is it ready for primetime?  AM J Med Sci. 338(6):486-492.  2009 December.
 
 
 
178. Bybee KA, Lee J, Markiewicz R, Longmore R, McGhie AI, O’Keefe JH, Hsu BL, Kennedy K, Thompson RC, Bateman TM:  Diagnostic and clinical benefit of combined coronary calcium and perfusion assessment in patients undergoing PET/CT myocardial perfusion stress imaging. J Nucl Cardiol. 17(2):188-196.  2010 April.
179. Main ML, Rao SC, O’Keefe JH:  Trends in obesity and extreme obesity among US adults.  JAMA. 30(17):1695 Author reply. 2010 May 5.
180. Lavie CJ, Milani RV, O’Keefe JH:  To B or Not to B:  Is non-high-density lipoprotein cholesterol an adequate surrogate for apolipoprotein B?  Mayo Clin Proc. 85(5):446-450.  2010 May.
181. Lavie CJ, Milani RV, O’Keefe JH:  Does the choice of statin really matter?  Postgrad Med;122(3):243-247. 2010 May.
182. Carter MD, Lee JH, Buchanan DM, Peterson ED, Tang F, Reid KJ, Spertus JA, Valtos J, O’Keefe JH:  Comparison of outcomes among moderate alcohol drinkers before acute myocardial infarction to effect of continued versus discontinuing alcohol intake after the infarct.  Epub 2010 April 24. Am J Cardio. 105(12):1651-1654.  2010 Jun.
183. Helzberg JH, Waeckerle JF, Camilo J, Selden MA Tang F, Joyce SA, Browne JE, O’Keefe JH:  Comparison of cardiovascular and metabolic risk factors in professional baseball players versus professional football players.  Am J Cardio.  106(5):664-667.  2010 September.
184. Helzberg JH, Camilo J, Waeckerle JF, O’Keefe JH:  Review of cardiometabolic risk factors among current professional football and professional baseball players.  Phys Sportsmed. 38(3):77-83. 2010 October.
185. Abuannadi M, O’Keefe JH, Brewer J:  Neckties for physicians: Yes? No? Maybe? With Pro/Con.  MO Med. 107(6):366-371. 2010 November/December.
186. O’Keefe JH, Abuannadi M:  Dietary strategies for the prevention and treatment of metabolic syndrome.  MO Med. 107(6):406-409. 2010 November/December.
187. O’Keefe JH, Vogel R, Lavie CJ, Cordain L:  Organic Fitness: Physical activity consistent with our hunter-gatherer heritage.  Phys Sportsmed. 38(4):11-18.  2010 December.
188. Abuannadi M, O’Keefe JH:  Eplerenone-An underutilized medication?  J Cardiovasc Pharmacol Ther. 15(4):318-325.  2010 December.
189. O’Keefe JH, Vogel R, Lavie CJ, Cordain L:  Achieving hunter-gatherer fitness in the 21(st) century: Back to the future.  Epub ahead of print 2010 September.   Am J Med.  123(12):1082-1086.  2010 December.   
190. O’Keefe JH, Abuannadi M, Lavie CJ, Bell DSH:  Strategies for optimizing glycemic control and cardiovascular prognosis in type 2 diabetes mellitus.  Mayo Clin Proc. 86(2):128-138.  2011 February. 
191. Singh PP, Abbott JD, Lombardero MS, Sutton-Tyrrell K, Woodhead G, Venkitachalam L, Tsapatsaris NP, Piemonte TC, Lago RM, Rutter MK, Nesto RW, BARI 2D Investigators: The prevalence and predictors of an abnormal ankle-brachial index in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial.  Diabetes Care. 34(2):464-467. PI for MAHI site.  2011 February.  
192. Carrera-Baston P, Fontes M, O’Keefe JH, Lindeberg L, Cordain L:  The Western diet and lifestyle and diseases of civilization.  Res Rpts Clin Cardio.  2(1):15-35. 2011 March.
193. Bell DSH, Al Badarin F, O’Keefe JH:  Therapies for diabetic dyslipidemia. Diabetes Obes Metab. 13(4):313-315.  2011 April.
194. Al Badarin F, Abuannadi MA, Lavie CJ, O’Keefe JH:  Evidence-based diuretic therapy for improving cardiovascular prognosis in systemic hypertension.  Am J Cardiol. 107(8):1178-1184.  2011 April 15.
195. Menezes A, Artham S, Lavie CJ, Milani RV, O’Keefe JH:  Erectile dysfunction and cardiovascular disease.  Postgraduate Med. 123(3):7-16. 2011 May.
196. Lavie CJ, Milani RV, O’Keefe JH:  Dyslipidemia intervention in metabolic syndrome – Emphasis on improving lipids and clinical event reduction.  Am J Med Sci. 341(5):388-393.  2011 May.  
197. Lavie CJ, Milani RV, O’Keefe JH, Lavie TJ:  Impact of exercise training on psychological risk factors.  Prog Cardiovasc Dis. 53(6):464-470.  2011 May-June.
198. O’Keefe JH, Vogel R, Lavie CJ, Cordain L:  Exercise like a hunter-gatherer: A prescription for organic physical fitness.  Prog Cardiovasc Dis. 53(6):471-479.  2011 May-June.
199. Conn RD, O’Keefe JH:  Reflections of Robert Conn on 50 years as a cardiologist.  Am J Cardiol.  107(11):1702-1704.  2011 June.
200. Lee JH, Gadi R, Spertus JA, Tang F, O’Keefe JH:  Prevalence of vitamin D deficiency in patients with acute myocardial infarction.  Am J Cardiol. 107(11):1636-1638.  2011 June.
201. Abuannadi M, O’Keefe JH:  Vitamin D and cardiovascular health.  PCCJ.  4(2):59-62.  2011 April/May/June.
202. Lee JH, Prasad A, Lavie CJ, Ventura H, Kay T, O’Keefe JH:  Nutritional assessment in heart failure patients.  Congest Heart Fail. 17(4):199-203. 2011 July.
203. Salisbury AC, Amin AP, Harris WS, Chan PS, Gosch KL, Rich MW, O’Keefe JH, Spertus JA: Predictors of omega-3 index in patients with acute myocardial infarction.  Mayo Clin Proc. 86(7):626-632. 2011 July.
204. Bell DS, O’Keefe JH:  Lowering the triglyceride/high-density lipoprotein cholesterol and its association with beneficial impact of pioglitazone on coronary artherosclerosis in the PERISCOPE Study is likely due to lowering insulin resistance. Letter to the Editor. J Am Coll Cardiol. 58(7):778. 2011 August.
205. Menezes AR, Lavie CJ, Milani RV, O’Keefe JH, Lavie TJ: Psychological risk factors and cardiovascular disease: Is it all in your head?  Postgrad Med. 123(5)1-12. 2011 September.
206. O’Keefe JH, Lavie CJ, Holick MF:  Vitamin D supplementation for cardiovascular disease prevention – Letter to the Editor.  JAMA. 306(14):1546-1547. 2011 October.
207. Patil H, Lavie CJ, O’Keefe JH: Cuppa Joe: Friend or Foe? Effects of chronic coffee consumption on cardiovascular and brain health. Mo Med. 108(6):431-438. 2011 November/December.
208. Wetmore JB, Gadi R, Lee JH, O’Keefe JH, Chan PS, Tang F, Spertus JA: Association of 25-hydroxyvitamin D deficiency with NT-pro BNP levels in patients with acute myocardial infarction: a cross-sectional analysis.  BMC Res Notes. 4(1):542. 2011 December.
209. Salisbury AC, Harris WS, Amin AP, Reid KJ, O’Keefe JH, Spertus JA: Relation between red blood cell omega-3 fatty acid index and bleeding during acute myocardial infarction.  Am J Cardiol. 109(1):13-18. 2012 January.
210. Lee JH, Chuu K, Spertus J, Cohen DJ, James AG, Tang F, O’Keefe JH:  Patients overestimate the potential benefits of elective percutaneous coronary intervention. Mo Med. 109(1):79-84. 2012 January/February.
211. O’Keefe JH, Patil HR, Lavie CJ:  Exercise and life expectancy.  Lancet. 3:379 (9818):799;author reply 800-801. 2012 March.
212. Lavie CJ,  Arena R, Church T, O’Keefe JH: The role of physical fitness in cardiovascular disease prevention. Med Roundtable Gen Med Ed. 1(2):152-163. 2012 March.
213. Conn RD, O’Keefe JH: Simplified evaluation of the jugular venous pressure: Significance of inspiratory collapse of jugular veins.  Mo Med. 209(2):150-152, 2012 March-April.
214. Al Badarin FJ, Lavie CJ, O’Keefe JH:  The last nail in the hydrochlorothiazide’s coffin?  Ochsner J. 12(1):4-6. 2012 Spring.
215. O’Keefe JH, Patil HR, Lavie CJ:  Can vitamin D deficiency break your heart?  Mayo Clin Proc. 87(4):412-413.  2012 April.
216. Patil HR, O’Keefe JH, Thompson RC, Bateman TM: Role of CT calcium scoring in screening for coronary artery disease.  Mo. Med. 109(3):193-193. 2012 May-June.
217. O’Keefe JH: When vigorous exercise becomes too much of a good thing.  Mo. Med. 109(3):192. 2012 May-June.
218. O’Keefe JH, Patil HR, Lavie, CJ, Magalski, A, Vogel RA, McCullough PA: Potential adverse cardiovascular effects from excessive endurance exercise.  Mayo Clin Proc. 87(6):587-95, 2012 June.
219. O’Keefe JH, Bybee KA, Lavie CJ, Hammill SC: ST-segment elevation: defined by the company it keeps. Mayo Clin Proc. 87(7):610-613. 2012 July.
220. Patil HR, O’Keefe JH, Lavie CJ, Magalski A, Vogel RA, McCullough PA: Cardiovascular damage resulting from chronic excessive endurance exercise.  Mo. Med. 109(4):312-321. 2012 July-August.
221. Menezes AR, Lavie CJ, Milani RV, O’Keefe JH:  The effects of statins on prevention of stroke and dementia: a review. J Cardiopulm Rehabil Prev. 32(5):240-249. 2012 September-October.
222. Patil H, Astik G, House JA, O’Keefe JH, Main ML: Prevalence of grade II and III obesity among patients hospitalized with cardiovascular diagnoses in 202 v 2009.  Mo. Med. 109(5):397-401. 2012 September-October.
223. Patil HR, Al Badarin FJ, Shami HA, Bhatti SK, Lavie CJ, Bell DS, O’Keefe JH: Meta-analysis of effect of dipeptidyl peptidase-4 inhibitors on cardiovascular risk in type 2 diabetes mellitus.  Am J Cardio. 110(6):826-833. Epub ahead of print 2012 June. 2012 September.
224. DiNicolantonio JJ, O’Keefe JH, Lavie CJ: Benefits and risks of aspirin use.  JAMA. 308(11):1088-1089. 2012 September.pii:S0167-5273(12)01182-5. Doi:10.1016/j.ijcard.2012.09.076.  Epub ahead of print.  2012 October.
225. DiNicolantonio JJ, O’Keefe JH, Lavie CJ: The big ones that got away: omega-3 meta-analysis flawed by excluding the biggest fish oil trials.  Arch Intern Med. 172(18):1427-1428. 2012 October.
 
226. Harris WS, Kennedy KF, O’Keefe JH, Spertus JA: Red blood cell fatty acid levels improve GRACE score prediction of 2-yr mortality in patients with myocardial infarction.  Int J Cardiol. Doi:pii:S0167-5273(12)01182-8. 10.1016/j.ijcard.2012.09.076. Epub ahead of print.  2012 October.
227. O’Keefe JH, Patil HR, Magalski A, Lavie CJ, Vogel RA, McCullough PA: Potential, but unobserved, adverse cardiovascular effects from endurance exercise – In Reply.  Mayo Clin Proc. 87(11):1133-1134.  2012 November.
228. Lavie CJ, DiNicolantonio JJ, O’Keefe JH, Milani RV: Vitamin D status, left ventricular geometric abnormalities and cardiovascular disease.  J Intern Med. Doi: 10.1111/joim.12009. Epub ahead of print. 2012 November.
229. O’Keefe JH, Lavie CJ:  Run for your life . . . at a comfortable speed and not too far.  Heart. Epub ahead of print.  PMID # 23197444.  2012 November.
230. Thompson RC, Patil H, Thompson EC, Thomas GS, Al-Amoodi M, Kennedy KF, Bybee KA, McGhie AI, O’Keefe JH, Oakes L, Bateman TM: Regadenoson pharmacologic stress for myocardial perfusion imaging: A three-way comparison between regadenoson administered at peak exercise, during walk recovery, or no exercise.  J Nucl Cardiol.  Epub ahead of print.  PMID# 23233371. 2012 December.
231. DiNicolantonio JJ, Lavie CJ, Fares H, Menezes AR, O’Keefe JH: Meta-analysis of carvediolol versus beta-1 selective beta-blockers (Atenolol, bisoprolol, Metoprolok, and Nebivolol).  Am J Cardiol. 20002-9149(12)2464-2.  Epub ahead of print.  2013 January.
 

On Staff At

  • Anderson County Hospital
  • Hedrick Medical Center
  • Saint Luke's Cushing Hospital
  • Saint Luke's East Hospital
  • Saint Luke's Hospital of Kansas City
  • Saint Luke's North Hospital–Barry Road
  • Saint Luke's North Hospital–Smithville
  • Saint Luke's South Hospital
  • Wright Memorial Hospital