Clinical Trials

Coronary Artery Disease

REvascularization Choices Among under-Represented Groups Evaluation (The RECHARGE Trial)

Breast Cancer

The effect of regular physical activity and virtual exercise intervention on physical functions, fatigue, mental health, and disease progression in Metastatic Breast Cancer (MBC)

Advanced Solid Tumors

First-in-Human Study of STX-478, a H1047X Mutation-specific PI3Kα Inhibitor as Monotherapy and in Combination with Other Antineoplastic Agents in Advanced Solid Tumor Patients Tumors

Postural Orthostatic Tachycardia Syndrome (POTS)

A Phase 2 Double-Blind Placebo-Controlled Single-Dose Study of Pharmacodynamics, Pharmacokinetics, Safety, and Tolerability of REGN7544, an NPR1 Antagonist Monoclonal Antibody, in Patients with Postural Orthostatic Tachycardia Syndrome

Women's Cardiovascular Health
Pregnancy Complications Leading to Cardiovascular Disease Outcomes Registry

Coronary Artery Disease
A randomized controlled study of the Prevail Drug-Coated Balloon in subjects with in-stent restenosis and a single arm prospectively enrolled study of the Prevail Drug-Coated Balloon for de novo lesions in small vessel disease (Prevail Global)

Cardiometabolic

A Phase III, Randomised, Double-blind, Placebo-controlled, Event-driven Study to Evaluate the Effect of Baxdrostat in Combination with Dapagliflozin Compared with Dapagliflozin Alone on the Risk of Incident Heart Failure and Cardiovascular Death in Participants with Increased Risk of Developing Heart Failure

Mitral Valve

Percutaneous or surgical Repair In Mitral prolapse And Regurgitation for ≥ 65 Year-olds

Heart Failure 
A Prospective, Multi-Center, Open Label, Randomized Control Clinical Trial Evaluating the Safety and Efficacy of the Cordella™ Pulmonary Artery Sensor System in New York Heart Association (NYHA) Class II -III Heart Failure Patients (PROACTIVE- HF-2 Trial)

Electrophysiology
Product Surveillance Registry (PSR) Platform Base Protocol

Aortic Stenosis

SAPIEN 3/SAPIEN 3 Ultra/SAPIEN 3 Ultra RESILIA Moderate AS PROGRESS Trial Access

Electrophysiology
Remote Alert Pathway To Optimize CaRe of Cardiac Implantable Electrical Devices

Pancreatic Cancer

RASolute 304: A Phase 3 Multicenter, Open-label, Randomized, 2-Arm Study of Adjuvant Daraxonrasib versus Observation Following Curative Intent Therapy in Patients with Resected Pancreatic Ductal Adenocarcinoma (PDAC)
 

Women's Cardiovascular Health

Randomized Evaluation of Bromocriptine in Myocardial Recovery Therapy for Peripartum Cardiomyopathy (REBIRTH)

Heart Failure 
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients (REDEFINE-HF)

Heart Failure 
RELIVE Trial- Randomized Evaluation of Less Invasive Ventricular Enhancement

Aortic Valve

RESTORE Study (REdo tranScatheter aortic valve replacement for Transcatheter aOrtic valve failuRE)
 

Neurology | Ischemic Stroke

Statins use in intracerebral hemorrhage patients

Advanced Solid Tumors

A Study of Disitamab Vedotin Alone or With Other Anticancer Drugs in Solid Tumors

Nursing | Post-ICU Delirium

Simultaneous Recumbent Cycling and Cognitive Training on Cognition in Intensive Care Unit Survivors: A Randomized Control Trial

Heart Failure 
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients with Advancing Heart Failure

Interventional Cardiology

A Pivotal, Prospective, Multicenter, 2:1 Randomized, Double Blind, Controlled Study Comparing the THerapeutIc IntraVasculaR Ultrasound (TIVUS™) REnal Denervation System vs. Sham for the Adjunctive Treatment of Hypertension (The THRIVE Study)

Structural

Transcatheter Mitral Valve Replacement with the INNOVALVE System Trial - Early Feasibility Study

Hypertension

The Global Paradise® System US Post Approval Study

Breast Cancer 
A Randomized, Open-Label, Phase 3 Study of Fulvestrant and CDK4/6 Inhibitors With or Without Gedatolisib as First-Line Treatment in Patients With HR-Positive and HER2-Negative Advanced Breast Cancer