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  • Saint Luke's Research
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  • Clinical Trials

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    Specialties

    • Cancer 28
    • Heart and Vascular 49
    • Neurosciences 4
    • Pulmonology 1
    • Surgery 8
    • Therapy and Rehabilitation 1

    Showing 26 - 50 out of 83 results

    Neurosciences

    Concussion Outcomes

    Concussion

    Neuropsychiatric Trajectories and Behavioral Health Outcomes Following Concussion in an Integrated Health System

    Contact Research Team: [email protected]
    Site principal investigator: Stephanie Kolakowsky-Hayner, PhD

    Heart and Vascular

    CONFIRMATION

    Heart Failure 
    A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients with Heart Failure (CONFIRMATION-HF)

    Contact Research Team: [email protected]
    Site principal investigator: Andrew Sauer, MD
    Learn more about this study:  NCT06024746

    Heart and Vascular

    COOL

    Women's Cardiovascular Health
    Monitoring outcomes for multidisciplinary care of women with cardiac disease in pregnancy: Creating a Cardio-Obstetrics Outcomes Log (COOL)

    Contact Research Team: [email protected]
    Site principal investigator: Anna Grodzinsky, MD

    Heart and Vascular

    COR-1389

    Cardiometabolic

    Phase 1b Randomized, Double-Blind, Placebo-Controlled Study of COR-1389 on Cardiopulmonary Hemodynamics in Patients with Pulmonary Hypertension Associated with Left-Heart Disease (PH-LHD)

    Contact Research Team: [email protected]
    Site principal investigator: Amrit Kanwar, MD

    Heart and Vascular

    Cosira II

    Myocardial Ischemia
    Efficacy of the COronary SInus Reducer in Patients with Refractory Angina II (COSIRA-II)

    Contact Research Team: [email protected]
    Site principal investigator: Anthony Hart, MD
    Learn more about this study: NCT05102019

    Heart and Vascular

    CTSN – EMBOLIC

    Cardiothoracic Surgery | Ischemic Stroke
    EMBOLIC PROTECTION IN PATIENTS UNDERGOING HIGH RISK VALVE SURGERY

    Contact Research Team: [email protected]
    Site principal investigator: Keith Allen, MD
    Learn more about this study: NCT06027788

    Cancer

    Elaine 3 SMX22002

    Breast Cancer

    Phase 3 open label study comparing efficacy and safety of the combination of lasofoxifene and abemaciclib to the combination of fulvestrant and abemaciclib for the treatment of adults with locally advanced or metastatic ER+/HER2- breast cancer with an ESR1 mutation

    Contact Research Team: [email protected]
    Site principal investigator: Timothy Pluard, MD
    Learn more about this study: NCT05696626

    ELEVATE

    Audiology | Cochlear Implant
    A pivotal, pre-market, prospective, interventional, multicenter study to evaluate clinical benefit, performance, and safety of the TI1132 implant in an adult population with sensorineural hearing loss

    Contact Research Team: [email protected]
    Site principal investigator: Robert Cullen, MD
    Learn more about this study: NCT07287124

    Heart and Vascular

    ELEVATE HFpEF

    Heart Failure 
    Randomized trial of ELEVATEd cardiac pacing rate for personalized treatment of Heart Failure with preserved Ejection Fraction (ELEVATEHFpEF)

    Contact Research Team: [email protected]
    Site principal investigator: Brian Ramza, MD
    Learn more about this study: NCT06678841

    Heart and Vascular

    ELEVATE III

    Interventional Cardiology
    THE MAGENTA ELEVATE™ HIGH-RISK PCI PIVOTAL STUDY

    Contact Research Team: [email protected]
    Site principal investigator: Dany Jacob, MD
    Learn more about this study: NCT07001332

    Cancer

    EmpowHER 303

    Breast Cancer 
    A Phase 3, randomized, open-label, multicenter, controlled study to evaluate the efficacy and safety of zanidatamab in combination with physician’s choice chemotherapy compared to trastuzumab in combination with physician’s choice chemotherapy for the treatment of participants with metastatic HER2-positive breast cancer who have progressed on, or are intolerant to, previous trastuzumab deruxtecan treatment

    Contact Research Team: [email protected]
    Site principal investigator: Timothy Pluard, MD
    Learn more about this study: NCT06435429

    Heart and Vascular

    ENVISION

    Aortic Stenosis
    Evaluation of the Navitor Transcatheter Heart Valve in Low and Intermediate Risk Patients who have Severe, Symptomatic, Aortic Stenosis Requiring Aortic Valve Replacement

    Contact Research Team: [email protected]
    Site principal investigator: Adnan Chhatriwalla, MD
    Learn more about this study: NCT05932615

    Cancer

    EXActDNA-003

    Breast Cancer

    Breast Cancer Clinical Validation Study to Predict Recurrence of High-Risk Early Breast Cancer Treated With Neoadjuvant Therapy Using a Bespoke Circulating Tumor DNA Assay to Detect Molecular Residual Disease

    Contact Research Team: [email protected]
    Site principal investigator: Whitney Hensing, MD
    Learn more about this study: NCT06401421

    Heart and Vascular

    Explanted Heart Valve Registry

    Valvular Diseases
    Explanted Heart Valve Registry

    Contact Research Team: [email protected]
    Site principal investigator: Keith Allen, MD

    Heart and Vascular

    FINALITY

    Heart Failure 
    A randomized, double-blind, placebo-controlled pragmatic study to evaluate FINerenone on clinicAL effIcacy and safeTY in patients with Heart Failure and reduced ejection fraction who are intolerant of or not eligible for treatment with steroidal mineralocorticoid receptor antagonists

    Contact Research Team: [email protected]
    Site principal investigator: Andrew Sauer, MD
    Learn more about this study: NCT06033950

    Pulmonology

    FROSTBITE 3

    Lung Cancer
    A Multicenter Randomized Trial of EBUS-TBNA Versus Transbronchial Mediastinal Cryobiopsy for Adequacy of Next Generation Sequencing

    Contact Research Team: [email protected]
    Site principal investigator: Salil Kulkarni, MD
    Learn more about this study: NCT06105801

    Neurosciences

    GRASP

    Neurology
    Vivistim Registry for Paired VNS Therapy (GRASP)

    Contact Research Team: [email protected]
    Site principal investigator: Stephanie Kolakowsky-Hayner, PhD
    Learn more about this study: NCT05301140

    Heart and Vascular

    HOPE

    Women's Cardiovascular Health | Pregnancy
    Heart Outcomes in Pregnancy Expectations (HOPE) for Mom and Baby

    Contact Research Team: [email protected]
    Site principal investigator: Anna Grodzinsky, MD
    Learn more about this study: NCT06517628

    Cancer

    IAMBIC IAM1363-01

    Breast Cancer 
    A Phase 1/1b Study of IAM1363 in Participants with Advanced Cancers Harboring HER2 Alterations

    Contact Research Team: [email protected]
    Site principal investigator: Timothy Pluard, MD
    Learn more about this study: NCT06253871

    Heart and Vascular

    IE in ACHD Registry

    Structural | Endocarditis
    INFECTIVE ENDOCARDITIS IN ADULTS WITH CONGENITAL HEART DISEASE: A REGISTRY

    Contact Research Team: [email protected]
    Site principal investigator: Christopher DeZorzi, MD

    Cancer

    INCA033890-303

    A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

    Contact Research Team: [email protected]
    Site principal investigator: Marc Roth, MD
    Learn more about this study: NCT07284849

    Heart and Vascular

    iSCAD

    Women's Cardiovascular Health
    iSCAD Registry

    Contact Research Team: [email protected]
    Site principal investigator: Anna Grodzinsky, MD
    Learn more about this study: NCT04496687

    Cancer

    IZABRIGHT-Breast01

    Breast Cancer
    A Randomized, Open-label, Inferentially Seamless Phase 2/3 Study of Izalontamab Brengitecan (BMS-986507) Versus Treatment of Physician's Choice in Patients With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer (TNBC) or ER-low, HER2-negative BC Who Are Ineligible for Anti-PD1/PD-L1 Treatment

    Contact Research Team: [email protected]
    Site principal investigator: Timothy Pluard, MD
    Learn more about this study: NCT06926868

    Heart and Vascular

    MaesTTRo

    Amyloidosis
    A Non-interventional, Prospective, Multi-country Study Collecting Realworld Data on the Characteristics, Treatment Patterns, and Outcomes of Patients with Amyloid Transthyretin (ATTR) Amyloidosis

    Contact Research Team: [email protected]
    Site principal investigator: Brett Sperry, MD
    Learn more about this study: NCT06465810

    Heart and Vascular

    MARITIME-HF

    Cardiometabolic
    Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity (MARITIME-HF)

    Contact Research Team: [email protected]
    Site principal investigator: Andrew Sauer, MD
    Learn more about this study: NCT07037459

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