Vulvar Cancer: Introduction

Cancer is when cells in the body change and grow out of control. To help you understand what happens when you have cancer, let's look at how your body works normally. Your body is made up of tiny building blocks called cells. Normal cells grow when your body needs them. They die when your body doesn't need them anymore.

Cancer is made up of abnormal cells that grow even though your body doesn't need them. In most cancers, the abnormal cells grow to form a lump or mass called a tumor. If cancer cells are in the body long enough, they can grow into (invade) nearby areas. They can even spread to other parts of the body (metastasize).

Nearly all vulvar cancers start in the squamous cells. This is called squamous cell carcinoma of the vulva. Squamous cells make up most of the skin and some other surfaces and linings of the body.

Other types of cancer that can start in the vulva include melanoma, basal cell carcinoma, adenocarcinoma, and sarcoma. This is rare.

The vulva is the outer part of the female reproductive system. It’s also called the external genitalia. The vulva is the fatty tissue and skin that's around the clitoris and the openings of the urethra (the tube that carries urine out of the body) and the vagina (birth canal). It includes:

• The mons pubis. This is the rounded area in front of the pubic bones. It becomes covered with hair at puberty.

• The 2 folds of skin on each side. The outer folds are called the labia majora. The inner folds are called the labia minora.

• The prepuce or the hood of the clitoris . This is made by the inner fold of the vulva.

• The clitoris is below the prepuce. It’s a sensitive piece of tissue that swells with blood when stimulated.

• The fourchette is at the bottom of the inner folds of the vulva. This is where the labia minora meet.

• The perineum is the area between the fourchette and the anus.

Most vulvar cancers start in the labia majora or the labia minora.

If you have questions about vulvar cancer, talk with your healthcare provider. Your provider can help you understand more about this cancer.