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Steven Tinkham was always proud of his active lifestyle. A born athlete, he grew up to find passion in biking and bodybuilding. But by the time he reached his 40s, an undiagnosed condition was beginning to take its toll—one joint at a time.

For three years, Linda Braxdale endured throbbing pain in her lower back and down her left leg. The pain and frustration often left her feeling helpless and defeated—and reduced to tears.

Shanon Wolfe's varicose vein troubles were more than cosmetic. Although her legs didn’t hurt at the end of the day, more and more often they felt heavy and tired. It began interfering with her kickboxing.