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Steven Tinkham was always proud of his active lifestyle. A born athlete, he grew up to find passion in biking and bodybuilding. But by the time he reached his 40s, an undiagnosed condition was beginning to take its toll—one joint at a time.

Beth O’Connor hoped the sharp, searing pain that started in her chest and shot down to her belly was labor pangs and not her aortic artery coming apart.

Shanon Wolfe's varicose vein troubles were more than cosmetic. Although her legs didn’t hurt at the end of the day, more and more often they felt heavy and tired. It began interfering with her kickboxing.