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Steven Tinkham was always proud of his active lifestyle. A born athlete, he grew up to find passion in biking and bodybuilding. But by the time he reached his 40s, an undiagnosed condition was beginning to take its toll—one joint at a time.

Kirsti Millar, a 35-year-old of Kansas City, was 23 weeks pregnant with her second child in early 2023 when her water suddenly broke. What should have been a season of joy and anticipation became a medical emergency.

Beth O’Connor hoped the sharp, searing pain that started in her chest and shot down to her belly was labor pangs and not her aortic artery coming apart.