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Steven Tinkham was always proud of his active lifestyle. A born athlete, he grew up to find passion in biking and bodybuilding. But by the time he reached his 40s, an undiagnosed condition was beginning to take its toll—one joint at a time.

When Debbie O’Neal was diagnosed with heart failure at 75, she feared her life was ending. She was the same age that her mother had been when she died of heart disease.

David Hartzler was the epitome of health. A former collegiate swimmer, he had continued the sport into adulthood. Three times a week, the Lawrence, Kan., resident swam 3,000 meters with the Lawrence Masters Swim Club.