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Steven Tinkham was always proud of his active lifestyle. A born athlete, he grew up to find passion in biking and bodybuilding. But by the time he reached his 40s, an undiagnosed condition was beginning to take its toll—one joint at a time.

When Debbie O’Neal was diagnosed with heart failure at 75, she feared her life was ending. She was the same age that her mother had been when she died of heart disease.

Chris Allen had so much pain in his legs that he couldn't walk 500 feet without needing to take a break. Now, he feels like he has two brand new wheels.