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Steven Tinkham was always proud of his active lifestyle. A born athlete, he grew up to find passion in biking and bodybuilding. But by the time he reached his 40s, an undiagnosed condition was beginning to take its toll—one joint at a time.

While chemotherapy, radiation, and surgeries are common for most cancer treatments, immunotherapy is continuing to allow some patients to forgo these often harsh and invasive methods altogether.

More than 10 years after his diagnosis, he’s helping other people with the same rare cancer to hold on to hope.

As 37-year-old Diamon Masterson watched his doctor study his CT scan results, he could tell from a puff of air that escaped the doctor’s mouth that the news was bad.